Multi Symptom

Frequently Asked Questions...

On the back of Formula 44 Multi-Symptom from Vicks, it says "Excitability may occur" what does that mean?

I was sick one day and took it, and while reading the drug facts and information, I noticed it said "Excitability may occur, especially in children" under the "When using this product" part. I was wondering just what exactly does that mean?


Answer:

It contains a stimulant (pseudoephedrine). This compound is related to meth but a much less potents CNS stimulant. So think of it as the warning on a can of Rockstar. However, the antihistamine in it could be a sedative (Chlorpheniramine). Which ever one has a greater impact on an individual will determine if they are "excitable" or "drowsy."

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Vicks DayQuil Cold Flu Multi Symptom Relief LiquiCaps 8 ea
$4.99
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Dristan Multi Symptom Nasal Decongestant Coated Tablets2 Pack SPECIAL
$20.86
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Childrens Triaminic Suspension Multi Symptom Fever Cold2 Pack SPECIAL
$19.30
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Nasacort Allergy 24 Hour Spray Multi Symptom For All Day Relief 3 PK 057 oz
$43.99
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Vicks Day Quil Cold and Flu Multi Symptom Relief 32 LiquiCaps Sealed Boxes
$12.66
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No Time for Colds Multi Symptom Cold Remedy Lozenges Lemon 18 Each 6 Pack
$30.49
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Vicks NyQuil Cold Flu Original Flavor Multi Symptom Relief Liquid 8 oz
$12.99
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Children Mucinex Multi Symptom Cold Age 4+ Very Berry 4Fl Oz
$8.99
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Midol Complete Multi Symptom Relief 16 count
$5.94
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Lot of 3 Robitussin Severe Multi Symptom Cough Cold + Flu 24 fl oz Tota FRESHl
$12.49
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2 Pamprin Maximum Multi Symptom Menstrual Relief 80 Caplets Total EXP02 2019
$15.99
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Mucinex Childrens Multi Symptom Cold Liquid 4 oz
$18.45
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Lot of 3 Robitussin Severe Multi Symptom Cough Cold + Flu 24 fl oz Total FRESH
$15.99
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2 Kaopectate Caplets Multi Symptom Relief Anti Diarrheal 56 Total EXP01 2020
$11.95
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Leader Adult Tussin Multi Symptom Cold Liquid 4oz 096295130409A299
$11.99
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Tylenol Cold Multi Symptom Nighttime 8oz 6 Pack 300450269089X476
$60.99
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Leader Adult Tussin Multi Symptom Cold Liquid 4oz 2 Pack 096295130409A299
$17.49
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Kirkland Signature DAYTIME NIGHTTIME COLD FLU MULTI SYMPTOM
$12.68
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Leader Adult Tussin Multi Symptom Cold Liquid 4oz 3 Pack 096295130409A299
$24.99
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Equate Adult Tussin CF Cold Multi Symptom 4 oz
$4.99
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Leader Adult Tussin Multi Symptom Cold Liquid 4oz 4 Pack 096295130409A299
$29.49
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DAYTIME MULTI SYMPTOM COLD FLU RELIEF Liquid Capsules NonDrowsy 10 Softgels
$2.99
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Coricidin HBP Nighttime Multi Symptom Cold Relief Liquid Cherry 10 Ounce
$37.20
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Mucinex Childrens Multi Symptom Cold Relief Liquid Very Berry 68oz
$21.01
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Leader Adult Tussin Multi Symptom Cold Liquid 4oz 5 Pack 096295130409A299
$33.99
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$43.99
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2 Pack Childrens Mucinex Multi Symptom Cold Very Berry 68 oz Each
$9.49
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Dristan Cold Tablets Multi Symptom 20 Tablets Pack of 2
$12.54
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Dristan Cold Tablets Multi Symptom 20 Tablets Pack of 3
$17.40
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Dristan Cold Tablets Multi Symptom 20 Tablets Pack of 5
$26.99
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$31.81
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$38.03
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Dristan Cold Tablets Multi Symptom 20 Tablets Pack of 8
$47.70
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$53.26
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Dristan Cold Tablets Multi Symptom 20 Tablets Pack of 4
$22.55
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Midol Max Caplets Size 16s Midol Meximum Strength Multi Symptom Menstrual Relief
$15.95
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6x QUALITY PLUS MULTI SYMPTOM COLD RELIEF DAYTIME NIGHTTIME 12 Caplets Each
$7.99
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Kirkland COLD Multi Symptom Daytime Non Drowsy Nighttime Severe Pain Reliever
$16.99
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Tukol X pecto Miel Multi Symptom Cold Natural Honey Miel Natural 4 oz
$8.88
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LOT OF 2 MUSINEX CHILDRENS MUCINEX MULTI SYMPTOM COLD 4 FLOZ EXP 10 2017
$7.99
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CVS Sinus PE Pressure Pain + Cough Multi Symptom 24 Caplets X 2
$0.99
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Kirkland COLD Multi Symptom Daytime Non Drowsy Nighttime Severe Pain Reliever
$14.88
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Mediqeu Medi First 82248 Multi Symptom Cold Relief Coated Tablets 125 Packets
$22.54
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4 Pk Robitussin Severe Multi Symptom Cough Cold+Flu Nighttime 4 Fl Oz Exp 4 17
$13.99
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2 Pk Robitussin Severe Multi Symptom Cough Cold+Flu Nighttime 4 Fl Oz Exp 10 17
$7.25
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3 Pk Robitussin Severe Multi Symptom Cough Cold+Flu Nighttime 4 Fl Oz Exp 6 17+
$10.49
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Boiron Chestal Homeopathic Cold Cough Multi Symptom Medicine for Age 3+ 67oz
$7.96
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3 Nasacort Nasal Allergy Spray 24 Hour Multi Symptom Strength 60 Sprays New
$20.99
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XL 3 Night Time Relief Cherry Flavor Multi symptom Xtreme Cold Flu Relief Max
$14.99
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Coricidin HBP Day Night Multi Symptom Cold Softgels Tablets 24 Tablets exp 04 17
$6.50
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10x Vicks Children NyQuil Cold Cough Multi Symptom Cherry 8 Oz EXP 09 2017
$25.49
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TYLENOL Cold Multi Symptom Caplets Daytime 24ct 2 Pack 300450271259T476
$20.49
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PediaCare Multi Symptom Cold plus Acetaminophen Liquid Gra2 Pack SPECIAL
$22.94
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$30.35
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$11.99
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$9.68
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$26.99
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$25.99
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$30.99
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$34.99
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$34.99
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6 Pk Mucinex Childrens Multi Symptom Cold and Fever Liquid 4 Fl Oz Exp 11 17
$28.49
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3 Pk Mucinex Childrens Multi Symptom Cold and Fever Liquid 4 Fl Oz Exp 4 17
$13.99
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Vicks DayQuil Cold Flu Multi Symptom Relief
$5.99
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4 Pk Mucinex Childrens Multi Symptom Cold and Fever Liquid 4 Fl Oz Exp 1 17
$17.49
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Imodium Advanced Multi Symptom Relief Caplets 18ct 5 Pack 300450212184T610
$62.99
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4 Pk Mucinex Childrens Multi Symptom Cold and Fever Liquid 4 Fl Oz Exp 7 17
$18.99
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2 pack Alka Seltzer Plus Multi Symptom Cold Flu Night 20 ct Gels EXP 6 2018
$8.99
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Pepto Bismol Multi Symptom Digestive Relief Medicine 40 Caplets Pack of 3
$23.55
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COLD EEZE Maximum Cold Flu Multi Symptom Relief Liquid 9 oz 106A
$10.99
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Tukol Multi Symptom Cold Maximum Strength Cough Syrup 4 fl oz Exp3 2018 Sealed
$9.77
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Mucinex Childrens Multi Symptom Cold Fever Liquid Berry2 Pack SPECIAL
$20.75
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Theraflu Multi Symptom Severe Cold Lipton Tea 12 Count
$6.29
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Kroger Adults Non drowsy Tussin CF Multi Symptom Cold 8fl oz 236 ml
$2.09
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NASACORT Allergy Multi Symptom Nasal Spray 24 Hour Relief 4 Individual Packs
$12.00
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CVS LOT OF 2 MULTI SYMPTOM SEVERE COLD 12 PACKETS GREEN TEA HONEY LEMON 5 18
$8.94
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Multi Symptom

rock you babe by multi-symptom

Fibromyalgia Symptom Treatment Priorities

Copyright 2010 Fibromyalgia Network

By Kristin Thorson

If patients could determine how symptoms might relate to one another, doctors might do a better job of individualizing care for people with fibromyalgia. For example, if pain is your number one treatment priority, what are the odds that you will want your physician to address issues related to sleep, fatigue, cognition, mood, or physical function? Also, are there any symptoms that tend to go hand in hand with one another (e.g., cluster together)? These are the types of questions that a recent study attempted to answer. *

"The presence and severity of a particular symptom may not necessarily equate with patients' preferences for its treatment," write the authors Robert M. Bennett, M.D., of Oregon Health and Sciences University, and I. Jon Russell, M.D., Ph.D., of the University of Texas at San Antonio. So this new study took a different approach. More than 750 fibromyalgia patients enrolled in a multi-center treatment trial for Lyrica agreed to also rank the top five symptoms (from a list of 20) that they would like to have treated. The list of 20 symptoms was developed by a previous research study involving fibromyalgia patient focus groups who were asked to describe their most relevant clinical features or symptoms.

Due to the large number of patients involved in this study, the researchers were able to apply statistical programs that mathematically determined which symptoms were most likely to cluster together. As a result, six cluster categories were identified: pain, fatigue, domestic, impairment, affective (mood-related), and social. Each individual cluster group and specific clinical features that tended to occur most related to one another (out of the 20) are shown in the table. As you will note, symptoms in the pain cluster were endorsed by the patients almost as frequently as those in the fatigue category (they differ by only 1 percent).

 

Symptom Treatment Priorities
... in order of selection frequency

Pain (90%)

  • Disturbed sleep
  • Pain or discomfort
  • Skin is sensitive to touch
  • Difficulty walking

Fatigue (89%)

  • Feeling tired
  • Difficulty thinking
  • Having to push yourself to do things
  • Having a lack of energy

Domestic (42%)

  • Difficulty being sexually intimate with your partner
  • Being unable to make plans with the confidence that you will follow-through
  • Strain on your relationship with spouse
  • Impact on your family

Impairment (29%)

  • Driving limitations
  • Interference with work or school
  • Interference with daily tasks

Mood-related or "Affective" (21%)

  • Feeling anxious
  • Feeling isolated
  • Feeling depressed

Social (9%)

  • Impact on your social life
  • Feeling like the pace of your life is slower than most other people

 

If you are wondering why disturbed sleep is in the pain rather than fatigue cluster, this is because the statistical analysis found pain and sleep to be more closely related. A patient who endorsed "disturbed sleep" was found to be 2.4 times more likely to also have endorsed "pain or discomfort" in their top five symptom treatment priorities.

"While pain and sleep have been suggested to have a reciprocal relationship in chronic pain conditions including fibromyalgia," write the authors, "our results raise the question as to whether pain causes disturbed sleep or pain is a result of disturbed sleep." Yet, difficulty thinking or fibro-fog clustered with symptoms of fatigue when it came to patients ranking their treatment priorities. In other words, a person wanting their fatigue to be treated was also more likely to request that attention be given to their fibro-fog.

Although the symptoms contained in the pain and fatigue clustered were virtually equal in terms of treatment priority for the group of 750 fibromyalgia patients, this was not the case for the other symptoms. "The psychosocial clusters were not considered to be as high a priority," write Bennett and Russell, adding that greater than 70 percent of the patients did not even rank the symptoms listed for these categories in their top five treatment priorities.

The many symptoms of fibromyalgia can certainly complicate the treatment of people with this disease and it would be beneficial for doctors (and their patients) if they could subgroup each patient according to how they rank the treatment of symptoms. As illustrated by this study, patients who want their pain treated will also probably want their physician to help with improving sleep. Patients who rank fatigue as the top symptom that they want treated will probably also want their fibro-fog addressed.

"Understanding the full complexity of the clinical features of fibromyalgia is becoming increasingly important with the availability of newer pharmacologic therapies that have significant effects on pain and other clinical features, such as sleep (Lyrica and Xyrem), affective symptoms (Cymbalta), and fatigue/fibro-fog (Savella)," write Bennett and Russell. As more studies like this one become published, the next step will be apply multi-drug therapies to target specific symptom clusters to determine how well subgrouping patients can improve their overall care.

* Bennett RM, et al. BMC Musculoskeletal Disorders 11:134-143, 2010.

About the Author

Kristin Thorson is at the forefront of fibromyalgia research, coping strategies, and latest treatment news. She is the chief editor and founder of the Fibromyalgia Network and founder of the American Fibromyalgia Syndrome Association(AFSA). As a fibro patient with a science background, she is able to translate everything from technical scientific findings to everyday practical suggestions and make them understandable to patients.

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